Leishmaniasis [Leishmania spp.]

Life cycle of Leishmania spp.

Leishmaniasis is transmitted by the bite of female phlebotomine sandflies. The sandflies inject the infective stage, promastigotes, during blood meals. Promastigotes in part on the Leishmania species. This originates the clinical manifestations of leishmaniasis. Sandflies become infected during blood meals on an infected host when they ingest macrophages infected with amastigotes. In the sandfly's midgut, the parasites differentiate into promastigotes, which multiply and migrate to the proboscis.

本图片是美国卫生及公共服务部旗下的美国疾病控制与预防中心的作品，系有关雇员作为其公务目的所拍摄或制作。作为美国联邦政府的作品，本图片属于公有领域。

Source: CDC; http://dpd.cdc.gov/dpdx/html/imagelibrary/Leishmaniasis_il.asp?body=G-L/Leishmaniasis/body_Leishmaniasis_il_th.htm.

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