File:Hepatitis B virus v2.svg
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描述Hepatitis B virus v2.svg |
English: Simplified graphical representation of a cross-section of the Hepatitis B virus particle and surface (surplus) antigen, the hepatitis B e antigens (HBcAg) shown are considered not part of the viral particle (quod vide viral nonstructural protein). The structure of the Hepatitis B virus as first described by Dane & al.[1] and Jokelainen, Krohn & al.[2] during 1970. The hepatitis B virion is a complex, double shelled, spherical particle with a 42 nm diameter.[1][2][3]
The virion was initially referred to as the Dane particle.[4] Only after Baruch Blumberg received the Nobel Prize in Medicine during 1976 was it universally accepted that the particle is a virus and the infectious agent of Hepatitis B.
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来源 | 基于如下对象的个人作品: Hepatitis B virus v2.png 2007年11月14日 (原始上传日期) Created by en:User:GrahamColm. Original uploader was TimVickers at en.wikipedia |
作者 | vectorization Glrx |
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- Hepatitis B core antigen (HBcAg) ≅ Hepatitis core antigen (Q24723361)
- 乙型肝炎核心抗原(Q24723361)
- Hepatitis B e antigen ≅ Hepatitis B e antigen (Q75838622)
- Hepatitis B e antigen(Q75838622)
- Hepatitis B surface antigen (HBsAg) ≅ HBsAg (Q2282887)
- B肝表面抗原(Q2282887)
- DNA polymerase ≅ DNA polymerase (Q206286)
- DNA聚合酶(Q206286)
- Partially double-stranded DNA ≅ DNA (Q7430)
- 脱氧核糖核酸(Q7430)
Sources
- ↑ a b c D.S. Dane , C.H. Cameron , Moya Briggs (1970). "Virus-Like Particles in Serum of Patients with Australia-Antigen-Associated Hepatitis". The Lancet 295: 695–698. DOI:10.1016/S0140-6736(70)90926-8.
- ↑ a b c d e f g h i j k l P. T. Jokelainen, Kai Krohn, A. M. Prince and N. D. C. Finlayson (1970). "Electron Microscopic Observations on Virus-Like Particles Associated with SH Antigen". Journal of Virology 6 (5): 685-689. ISSN 1098-5514.
- ↑ a b c d e f The hepatitis B virus. World Health Organisation.
- ↑ a b Almeida J D, Rubenstein D & Scott E J. (1971). "New antigen-antibody system in Australia-antigen-positive hepatitis". The Lancet 298 (7736): 1225–7. DOI:10.1016/S0140-6736(71)90543-5.
- ↑ Bayer, M. E., B. S. Blumberg, and B. Werner (1968). "Particles associated with Australia antigen in the sera of patients with leukemia, Down's syndrome and hepatitis.". Nature (London) 218: 1057-1059.
- ↑ Baruch S. Blumberg, Harvey J. Alter, and Sam Visnich (Jul 1984). "Landmark article Feb 15, 1965: A 'new' antigen in leukemia sera. By Baruch S. Blumberg, Harvey J. Alter, and Sam Visnich". Journal of the American Medical Association 252 (2): 252–7. DOI:10.1001/jama.252.2.252. PMID 6374187. ISSN 0098-7484.
- ↑ Prince, A. M. (1968). "An antigen detected in the blood during the incubation period of serum hepatitis". Proceedings of the National Academy of Science U.S.A. 60: 814-821.
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