Template:PBB/3251

次黃嘌呤-鳥嘌呤磷酸核苷轉移酶 Hypoxanthine phosphoribosyltransferase 1
Ribbon diagram of a human HPRT tetramer. Magnesium ions visible in green. From PDB 1BZY.
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 1BZY, 1D6N, 1HMP, 1Z7G, 2VFA, 3GEP, 3GGC, 3GGJ, 4IJQ, 4KN6
标识
代号	HPRT1; HGPRT; HPRT
扩展标识	遗传学：308000 鼠基因：96217 同源基因：56590 ChEMBL: 2360 GeneCards: HPRT1 Gene
EC編號	2.4.2.8
基因本体论描述 分子功能 · nucleotide binding · magnesium ion binding · hypoxanthine phosphoribosyltransferase activity · protein binding · protein homodimerization activity · guanine phosphoribosyltransferase activity 细胞成分 · cytoplasm · cytosol · extracellular vesicular exosome 生物过程 · response to amphetamine · purine nucleobase metabolic process · purine nucleotide biosynthetic process · purine ribonucleoside salvage · adenine salvage · guanine salvage · grooming behavior · locomotory behavior · cytolysis · striatum development · cerebral cortex neuron differentiation · central nervous system neuron development · GMP salvage · IMP salvage · dopamine metabolic process · purine-containing compound salvage · hypoxanthine salvage · small molecule metabolic process · positive regulation of dopamine metabolic process · GMP catabolic process · IMP metabolic process · hypoxanthine metabolic process · lymphocyte proliferation · dendrite morphogenesis · protein homotetramerization · nucleobase-containing small molecule metabolic process Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	3251	15452
Ensembl	ENSG00000165704	ENSMUSG00000025630
UniProt	P00492	P00493
mRNA序列	NM_000194	NM_013556
蛋白序列	NP_000185	NP_038584
基因位置	Chr X: 133.59 – 133.65 Mb	Chr X: 52.99 – 53.02 Mb
PubMed查询	[1]	[2]