CD80
CD80（英语：Cluster of Differentiation 80，分化群80，也称为B7-1）是一个位于3号染色体的人类基因，属于免疫球蛋白超家族中的B7蛋白质家族[7]，在树突状细胞、活化的B细胞、巨噬细胞以及T细胞上表达[8]，与CD86（也称为B7-2）形成共刺激信号[9]。
参考文献
[编辑]- ^ 與CD80相關的疾病；在維基數據上查看/編輯參考.
- ^ 對CD80 molecule起作用的藥物；在維基數據上查看/編輯參考.
- ^ 3.0 3.1 3.2 GRCh38: Ensembl release 89: ENSG00000121594 - Ensembl, May 2017
- ^ 4.0 4.1 4.2 GRCm38: Ensembl release 89: ENSMUSG00000075122 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mir MA. Introduction to Costimulation and Costimulatory Molecules. Developing Costimulatory Molecules for Immunotherapy of Diseases (Elsevier). 2015: 1–43. ISBN 978-0-12-802585-7. doi:10.1016/b978-0-12-802585-7.00001-7.
- ^ CD80 - T-lymphocyte activation antigen CD80 precursor - Homo sapiens (Human) - CD80 gene & protein. www.uniprot.org. [2021-06-09] （英语）.
- ^ Peach RJ, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley PS. Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28. The Journal of Biological Chemistry. September 1995, 270 (36): 21181–7. PMID 7545666. doi:10.1074/jbc.270.36.21181
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外部链接
[编辑]- Human CD80 genome location and CD80 gene details page in the UCSC Genome Browser.