4-甲氧基雌酮
| 4-甲氧基雌酮 | |
|---|---|
| |
| IUPAC名 (8R,9S,13S,14S)-3-Hydroxy-4-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one | |
| 別名 | 4-ME1; 4-MeOE1; 4-MeO-E1; 4-Hydroxyestrone 4-methyl ether; 3-Hydroxy-4-methoxyestra-1,3,5(10)-trien-17-one |
| 識別 | |
| CAS號 | 58562-33-7 
|
| PubChem | 194066 |
| ChemSpider | 168393 |
| SMILES |
|
| ChEBI | 136972 |
| 性質 | |
| 化學式 | C19H24O3 |
| 摩爾質量 | 300.39 g·mol−1 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
4-甲氧基雌酮（英語：4-Methoxyestrone，縮寫4-ME1）是一種天然內源性的甲氧基化的兒茶酚雌激素和雌酮的代謝產物，在體內通過兒茶酚-O-甲基轉移酶（COMT）催化中間體4-羥基雌酮生成[1][2][3]，其雌激素活性近似雌酮和4-羥基雌酮[4]。
參考資料
[編輯]- ^ 存档副本. [2021-01-28]. （原始內容存檔於2017-01-01）.
- ^ Hemnes AR. Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide. Humana Press. 16 December 2015: 32–. ISBN 978-3-319-23998-9.
- ^ Lauritzen C, Studd JW. Current Management of the Menopause. CRC Press. 22 June 2005: 378–379. ISBN 978-0-203-48612-2.
- ^ Bhavnani BR, Nisker JA, Martin J, Aletebi F, Watson L, Milne JK. Comparison of pharmacokinetics of a conjugated equine estrogen preparation (premarin) and a synthetic mixture of estrogens (C.E.S.) in postmenopausal women. Journal of the Society for Gynecologic Investigation. 2000, 7 (3): 175–83. PMID 10865186. doi:10.1016/s1071-5576(00)00049-6.