煙酸鹽酸鹽

煙酸鹽酸鹽
英文名	Nicotinic acid hydrochloride; Niacin hydrochloride
別名	3-吡啶甲酸鹽酸鹽
識別
CAS號	636-79-3
SMILES	OC(=O)c1c[nH+]ccc1.[Cl-];
性質
化學式	C6H6ClNO2
摩爾質量	159.57 g·mol−1
外觀	晶體
熔點	250—255 °C（523—528 K）
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

煙酸鹽酸鹽是一種化合物，化學式為C₆H₆ClNO₂，它由質子化的煙酸陽離子（C₆H₆NO₂⁺）和氯離子構成，分子間存在O－H…Cl、N－H…O和N－H…Cl氫鍵。^[2]它可由煙酸的甲醇溶液和鹽酸的甲醇溶液反應得到。^[2]它可以在鉑的催化下於50 °C加壓氫化，得到3-哌啶甲酸鹽酸鹽。^[3]

參考文獻

^ Wibaut, J. P.; Beyerman, H. C. The constitution of dihydronicotyrine (N-methylmyosmine). Recueil des Travaux Chimiques des Pays-Bas et de la Belgique, 1951. 70: 977-984. ISSN: 0370-7539.
^ ^2.0 ^2.1 Slouf, Miroslav. 3-Carboxypyridinium chloride. Acta Crystallographica Section E Structure Reports Online. 2000, 57 (1): o61–o62. ISSN 1600-5368. doi:10.1107/S1600536800019632.
^ Karpov, A. A.; Krasnikov, S. V.; Betnev, A. F.; Krasovskaya, G. G.; Chal'tsev, A. V. Catalytic hydrogenation of 2-furan- and 2- and 3-pyridinecarboxylic acids. Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya, 2007. 4: 44-46. ISSN: 0579-2991.
^ Yoshino, Teruo; Inaba, Shigeru; Komura, Hajime; Ishido, Yoshiharu. Synthetic Studies by the Use of Carbonates. I. The Nucleophilic Substitution Reaction of Ethylene Carbonate with Amine Hydrohalides. Bulletin of the Chemical Society of Japan. 1974, 47 (2): 405–409. ISSN 0009-2673. doi:10.1246/bcsj.47.405.
^ Goher, Mohamed A. S.; Mautner, Franz A.; Mak, Thomas C. W.; Abu-Youssef, Morsy A. M. Synthesis and Crystal Structures of [(Nicotinic Acid)2H]+I−, [(2-Amino-6-methylpyridine)H]+(NO3)?, and the 1:1 Complex Between 1-Isoquinoline Carboxylic Acid (Zwitter Ion) and L-Ascorbic Acid Assembled via Hydrogen Bonds. Monatshefte für Chemie / Chemical Monthly. 2003, 134 (12): 1519–1527. ISSN 0026-9247. doi:10.1007/s00706-003-0054-9.

[1] Wibaut, J. P.; Beyerman, H. C. The constitution of dihydronicotyrine (N-methylmyosmine). Recueil des Travaux Chimiques des Pays-Bas et de la Belgique, 1951. 70: 977-984. ISSN: 0370-7539.

[Slouf2000-2] 2.0 ^2.1 Slouf, Miroslav. 3-Carboxypyridinium chloride. Acta Crystallographica Section E Structure Reports Online. 2000, 57 (1): o61–o62. ISSN 1600-5368. doi:10.1107/S1600536800019632.

[3] Karpov, A. A.; Krasnikov, S. V.; Betnev, A. F.; Krasovskaya, G. G.; Chal'tsev, A. V. Catalytic hydrogenation of 2-furan- and 2- and 3-pyridinecarboxylic acids. Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya, 2007. 4: 44-46. ISSN: 0579-2991.

[4] Yoshino, Teruo; Inaba, Shigeru; Komura, Hajime; Ishido, Yoshiharu. Synthetic Studies by the Use of Carbonates. I. The Nucleophilic Substitution Reaction of Ethylene Carbonate with Amine Hydrohalides. Bulletin of the Chemical Society of Japan. 1974, 47 (2): 405–409. ISSN 0009-2673. doi:10.1246/bcsj.47.405.

[5] Goher, Mohamed A. S.; Mautner, Franz A.; Mak, Thomas C. W.; Abu-Youssef, Morsy A. M. Synthesis and Crystal Structures of [(Nicotinic Acid)2H]+I−, [(2-Amino-6-methylpyridine)H]+(NO3)?, and the 1:1 Complex Between 1-Isoquinoline Carboxylic Acid (Zwitter Ion) and L-Ascorbic Acid Assembled via Hydrogen Bonds. Monatshefte für Chemie / Chemical Monthly. 2003, 134 (12): 1519–1527. ISSN 0026-9247. doi:10.1007/s00706-003-0054-9.

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相關物質

參考文獻