3-氯吡啶

3-氯吡啶
英文名	3-chloropyridine
識別
CAS號	626-60-8
SMILES	n1cc(Cl)ccc1;
性質
化學式	C5H4ClN
摩爾質量	113.54 g·mol⁻¹
密度	1.200±0.06 g·cm-3
熔點	135 °C（408 K）
沸點	148 °C（421 K）
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

3-氯吡啶是一種有機化合物，化學式為C₅H₄ClN。它的同分異構體有2-氯吡啶和4-氯吡啶。該化合物可用作醫藥中間體。^[3]3-氯吡啶在鹼性條件下和金屬在鎳催化劑的存在下可以發生偶合反應，得到3,3'-聯吡啶。^[4]^[5]其鋰化反應得到有機鋰化合物，可以用作相對難於得到的其它吡啶衍生物的前體。^[6]

參考文獻

^ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2018 ACD/Labs). Retrieved from SciFinder. [2018-6-27]
^ Kamienski, B.; Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques 1965, V13(9), P643-8 CAPLUS
^ 3-氯吡啶（頁面存檔備份，存於互聯網檔案館）. Chemical Book. [2018-6-26]
^ Yves Fort, Sandrine Becker, Paul Caubère. A convenient synthetic route to bis-heteroaromatic and bis-heterocyclic compounds promoted by liganded nickel complex reducing agents.. Tetrahedron. 1994-01, 50 (41): 11893–11902 [2018-06-26]. ISSN 0040-4020. doi:10.1016/s0040-4020(01)89303-0. （原始內容存檔於2018-06-04）.
^ E. Rajalakshmanan, V. Alexander. Synthesis of Dimethylbipyridines by the Reductive Coupling of 2‐Halomethylpyridines with Nickel Catalyst. Synthetic Communications. 2005-03, 35 (6): 891–895. ISSN 0039-7911. doi:10.1081/scc-200051056.
^ J. A. Joules, K. Mills: Heterocyclic Chemistry, 5. Auflage, S. 125–141, Blackwell Publishing, Chichester, 2010, ISBN 978-1-4051-9365-8.

[1] Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2018 ACD/Labs). Retrieved from SciFinder. [2018-6-27]

[2] Kamienski, B.; Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques 1965, V13(9), P643-8 CAPLUS

[3] 3-氯吡啶（頁面存檔備份，存於互聯網檔案館）. Chemical Book. [2018-6-26]

[4] Yves Fort, Sandrine Becker, Paul Caubère. A convenient synthetic route to bis-heteroaromatic and bis-heterocyclic compounds promoted by liganded nickel complex reducing agents.. Tetrahedron. 1994-01, 50 (41): 11893–11902 [2018-06-26]. ISSN 0040-4020. doi:10.1016/s0040-4020(01)89303-0. （原始內容存檔於2018-06-04）.

[5] E. Rajalakshmanan, V. Alexander. Synthesis of Dimethylbipyridines by the Reductive Coupling of 2‐Halomethylpyridines with Nickel Catalyst. Synthetic Communications. 2005-03, 35 (6): 891–895. ISSN 0039-7911. doi:10.1081/scc-200051056.

[6] J. A. Joules, K. Mills: Heterocyclic Chemistry, 5. Auflage, S. 125–141, Blackwell Publishing, Chichester, 2010, ISBN 978-1-4051-9365-8.

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