1,4-二氯丁烷

1,4-二氯丁烷
识别
CAS号	110-56-5
PubChem	8059
SMILES	ClCCCCCl;
性质
化学式	C4H8Cl2
摩尔质量	127.01 g·mol−1
外观	无色液体
密度	1.1324 g·cm−3（25 °C）
熔点	−37.3 °C（235.8 K）
沸点	161 °C（434 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

1,4-二氯丁烷是一种有机化合物，化学式为C₄H₈Cl₂，它是二氯丁烷的同分异构体之一。它可由1,4-丁二醇和氯化试剂（如光气^[3]、氯化亚砜^[4]、四氯化碳^[5]）反应得到。它和咪唑在氢化钠的存在下反应，可以得到1,4-二(1-咪唑基)丁烷。^[6]

1,4-二氯丁烷是生产尼龙的前体。^[7]^[8]

参考文献

^ Herbert C. Brown, Arthur B. Asii. Isomer Distribution in the Sulfuryl Chloride Chlorination of the 1-Chlorobutanes and Related Compounds; the Inductive Effect in Free Radical Substitutions 1. Journal of the American Chemical Society. 1955-08, 77 (15): 4019–4024 [2020-11-30]. ISSN 0002-7863. doi:10.1021/ja01620a019 （英语）.
^ ^2.0 ^2.1 "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2020-11-30].
^ Ettl, Roland; Reuther, Wolfgang. Preparation of alkyl chlorides from the corresponding alcohols. 1995. EP 645357 A1.
^ F. D. Gunstone, P. J. Sykes. 590. Fatty acids. Part VII. The synthesis of hexadeca-8,10-dienoic, octadeca-7,11-dienoic, and eicosa-7,13-dienoic acid. Journal of the Chemical Society (Resumed). 1962: 3055 [2020-11-30]. ISSN 0368-1769. doi:10.1039/jr9620003055 （英语）.
^ Ravil I. Khusnutdinov, Alfiya R. Bayguzina, Rigina S. Asylbaeva, Rishat I. Aminov, Usein M. Dzhemilev. Synthesis of N-aryl-substituted pyrrolidines and piperidines by reaction of anilines with α,ω-diols catalyzed by FeCl3.6H2O in carbon tetrachloride. Arkivoc. 2014-09-13, 2014 (5): 341–350 [2020-11-30]. ISSN 1551-7012. doi:10.3998/ark.5550190.p008.743. （原始内容存档于2020-11-26）（英语）.
^ Nader Ghaffari Khaligh, Taraneh Mihankhah, Mohd Rafie Johan, Juan Joon Ching. Two novel binuclear sulfonic-functionalized ionic liquids: Influence of anion and carbon-spacer on catalytic efficiency for one-pot synthesis of bis(indolyl)methanes. Journal of Molecular Liquids. 2018-06, 259: 260–273 [2020-11-30]. doi:10.1016/j.molliq.2018.03.044 （英语）.
^ Mark S. M. Alger. Polymer Science Dictionary. Springer. 1997: 241 [August 28, 2008]. ISBN 0-412-60870-7. Google Book Search. （原始内容存档于2022-12-27）.
^ Rossberg, Manfred; Lendle, Wilhelm; Pfleiderer, Gerhard; Tögel, Adolf; Dreher, Eberhard-Ludwig; Langer, Ernst; Rassaerts, Heinz; Kleinschmidt, Peter; Strack, Chlorinated Hydrocarbons, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a06_233.pub2

[1] Herbert C. Brown, Arthur B. Asii. Isomer Distribution in the Sulfuryl Chloride Chlorination of the 1-Chlorobutanes and Related Compounds; the Inductive Effect in Free Radical Substitutions 1. Journal of the American Chemical Society. 1955-08, 77 (15): 4019–4024 [2020-11-30]. ISSN 0002-7863. doi:10.1021/ja01620a019 （英语）.

[SRC-2] 2.0 ^2.1 "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2020-11-30].

[3] Ettl, Roland; Reuther, Wolfgang. Preparation of alkyl chlorides from the corresponding alcohols. 1995. EP 645357 A1.

[4] F. D. Gunstone, P. J. Sykes. 590. Fatty acids. Part VII. The synthesis of hexadeca-8,10-dienoic, octadeca-7,11-dienoic, and eicosa-7,13-dienoic acid. Journal of the Chemical Society (Resumed). 1962: 3055 [2020-11-30]. ISSN 0368-1769. doi:10.1039/jr9620003055 （英语）.

[5] Ravil I. Khusnutdinov, Alfiya R. Bayguzina, Rigina S. Asylbaeva, Rishat I. Aminov, Usein M. Dzhemilev. Synthesis of N-aryl-substituted pyrrolidines and piperidines by reaction of anilines with α,ω-diols catalyzed by FeCl3.6H2O in carbon tetrachloride. Arkivoc. 2014-09-13, 2014 (5): 341–350 [2020-11-30]. ISSN 1551-7012. doi:10.3998/ark.5550190.p008.743. （原始内容存档于2020-11-26）（英语）.

[6] Nader Ghaffari Khaligh, Taraneh Mihankhah, Mohd Rafie Johan, Juan Joon Ching. Two novel binuclear sulfonic-functionalized ionic liquids: Influence of anion and carbon-spacer on catalytic efficiency for one-pot synthesis of bis(indolyl)methanes. Journal of Molecular Liquids. 2018-06, 259: 260–273 [2020-11-30]. doi:10.1016/j.molliq.2018.03.044 （英语）.

[7] Mark S. M. Alger. Polymer Science Dictionary. Springer. 1997: 241 [August 28, 2008]. ISBN 0-412-60870-7. Google Book Search. （原始内容存档于2022-12-27）.

[Ullmann-8] Rossberg, Manfred; Lendle, Wilhelm; Pfleiderer, Gerhard; Tögel, Adolf; Dreher, Eberhard-Ludwig; Langer, Ernst; Rassaerts, Heinz; Kleinschmidt, Peter; Strack, Chlorinated Hydrocarbons, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a06_233.pub2

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