尿激酶受體
外觀
尿激酶受體(英語:Urokinase receptor,或稱為尿纖溶酶原活化物受體,縮寫uPAR,也稱為CD87,Cluster of Differentiation 87,分化簇87)是一種多結構域醣蛋白,通過糖磷脂醯肌醇(GPI)錨定在細胞膜上,最初被鑑定為尿激酶(尿纖溶酶原活化物,uPA)在細胞表面的飽和結合位點。uPAR在多種癌細胞表明都有發現[5]。
參考文獻
[編輯]- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000011422 - Ensembl, May 2017
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000046223 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Smith, HW; Marra, P; Marshall, CJ. uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.. The Journal of cell biology. 2008-08-25, 182 (4): 777–90. PMID 18725541. doi:10.1083/jcb.200712050.
外部連結
[編輯]- 醫學主題詞表(MeSH):PLAUR+protein,+human
- PDB中UniProt可用的所有結構資訊之概述:Q03405 (Human Urokinase plasminogen activator surface receptor) 在PDBe-KB。