UCP2

UCP2
識別號
別名	UCP2；, BMIQ4, SLC25A8, UCPH, uncoupling protein 2
外部ID	OMIM：601693 MGI：109354 HomoloGene：2516 GeneCards：UCP2
基因位置（人類）
染色體	11號染色體
終止	73,983,246 bp
基因位置（小鼠）
染色體	小鼠7號染色體
終止	100,151,227 bp
RNA表現模式
	; ;
	查閱更多表現資料
基因本體
分子功能	• 血漿蛋白結合; • oxidative phosphorylation uncoupler activity; • transmembrane transporter activity;
細胞組分	• 細胞質; • 膜; • mitochondrial membranes; • mitochondrial inner membrane; • integral component of membrane; • 粒線體;
生物學過程	• positive regulation of cell death; • response to hypoxia; • response to superoxide; • response to fatty acid; • female pregnancy; • cellular response to amino acid starvation; • negative regulation of insulin secretion involved in cellular response to glucose stimulus; • 老化; • negative regulation of apoptotic process; • response to glucose; • regulation of mitochondrial membrane potential; • liver regeneration; • cellular response to hormone stimulus; • cellular response to insulin stimulus; • cellular response to glucose stimulus; • response to cold; • mitochondrial transmembrane transport; • adaptive thermogenesis; • mitochondrial transport; • proton transmembrane transport; • positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
直系同源
	7351
	22228
	ENSG00000175567
	ENSMUSG00000033685
	P55851
	P70406
	NM_003355
	NM_011671
NP_003346; NP_001368872; NP_001368873; NP_001368874; NP_001368876;
	NP_001368877; NP_001368878; NP_001368879
	NP_035801
	維基資料
檢視/編輯人類	檢視/編輯小鼠

粒線體解偶聯蛋白2是一種在人類中由UCP2基因編碼的蛋白。粒線體解偶聯蛋白是粒線體陰離子載體蛋白大家族的成員。UCP通過將粒線體膜電位耗散為熱量（也稱為粒線體質子洩漏），從而將氧化磷酸化與ATP合成分離或分離。UCP促進陰離子從粒線體內膜轉移到粒線體外膜，並促進質子從粒線體外膜返回到粒線體內膜。

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000175567 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033685 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000175567 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033685 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

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