4-羟基苯甲醛

4-羟基苯甲醛
	IUPAC名; 4-Hydroxybenzaldehyde
别名	对羟基苯甲醛
识别
CAS号	123-08-0
PubChem	126
ChemSpider	123
SMILES	O=Cc1ccc(O)cc1;
InChI	1/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H;
InChIKey	RGHHSNMVTDWUBI-UHFFFAOYAN
ChEBI	17597
DrugBank	DB03560
KEGG	C00633
性质
化学式	C7H6O2
摩尔质量	122.12 g·mol−1
外观	浅黄色粉末
密度	1.226 ± 0.06 g/cm3
熔点	112—116 °C（385—389 K）
沸点	310—311 °C（583—584 K）
磁化率	-78.0·10−6 cm3/mol
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

4-羟基苯甲醛是一种有机化合物，化学式为C₇H₆O₂，存在于天麻兰^[1]、山珊瑚^[2]和香荚兰中。它可由4-羟基苯甲醇的催化氧化反应制得。^[3]^[4]它和乙酸酐反应，可以得到4-乙酰氧基苯甲醛。^[5]

参考文献

^ Ha, J. H.; Lee, D. U.; Lee, J. T.; Kim, J. S.; Yong, C. S.; Kim, J. A.; Ha, J. S.; Huh, K. 4-Hydroxybenzaldehyde from Gastrodia elata B1. Is active in the antioxidation and GABAergic neuromodulation of the rat brain. Journal of Ethnopharmacology. 2000, 73 (1–2): 329–333. PMID 11025174. doi:10.1016/S0378-8741(00)00313-5.
^ Li, Y. M.; Zhou, Z. L.; Hong, Y. F. (title in Chinese) [Studies on the phenolic derivatives from Galeola faberi Rolfe]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 1993, 28 (10): 766–771. PMID 8009989 （中文）.
^ SyedF. Adil, MohamedE. Assal, Mufsir Kuniyil, Mujeeb Khan, Mohammed Rafi Shaik, Abdulrahman Alwarthan, JoselitoP. Labis, Mohammed RafiqH. Siddiqui. Synthesis and comparative catalytic study of zinc oxide (ZnO x ) nanoparticles promoted MnCO 3 , MnO 2 and Mn 2 O 3 for selective oxidation of benzylic alcohols using molecular oxygen. Materials Express. 2017-04-01, 7 (2): 79–92 [2021-05-21]. ISSN 2158-5849. doi:10.1166/mex.2017.1357 （英语）.
^ Eduardo Buxaderas, Marilyn Graziano-Mayer, María Volpe, Gabriel Radivoy. Bimetallic Cu-Pd Nanoparticles Supported on Bio-silica as an Efficient Catalyst for Selective Aerobic Oxidation of Benzylic Alcohols. Synthesis. 2016-10-21, 49 (06): 1387–1393 [2021-05-21]. ISSN 0039-7881. doi:10.1055/s-0036-1588628. （原始内容存档于2018-06-02）（英语）.
^ Karol Kraszewski, Ireneusz Tomczyk, Aneta Drabinska, Krzysztof Bienkowski, Renata Solarska, Marcin Kalek. Mechanism of Iodine(III)‐Promoted Oxidative Dearomatizing Hydroxylation of Phenols: Evidence for a Radical‐Chain Pathway. Chemistry – A European Journal. 2020-09-04, 26 (50): 11584–11592 [2021-05-21]. ISSN 0947-6539. doi:10.1002/chem.202002026 （英语）.

[1] Ha, J. H.; Lee, D. U.; Lee, J. T.; Kim, J. S.; Yong, C. S.; Kim, J. A.; Ha, J. S.; Huh, K. 4-Hydroxybenzaldehyde from Gastrodia elata B1. Is active in the antioxidation and GABAergic neuromodulation of the rat brain. Journal of Ethnopharmacology. 2000, 73 (1–2): 329–333. PMID 11025174. doi:10.1016/S0378-8741(00)00313-5.

[2] Li, Y. M.; Zhou, Z. L.; Hong, Y. F. (title in Chinese) [Studies on the phenolic derivatives from Galeola faberi Rolfe]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 1993, 28 (10): 766–771. PMID 8009989 （中文）.

[3] SyedF. Adil, MohamedE. Assal, Mufsir Kuniyil, Mujeeb Khan, Mohammed Rafi Shaik, Abdulrahman Alwarthan, JoselitoP. Labis, Mohammed RafiqH. Siddiqui. Synthesis and comparative catalytic study of zinc oxide (ZnO x ) nanoparticles promoted MnCO 3 , MnO 2 and Mn 2 O 3 for selective oxidation of benzylic alcohols using molecular oxygen. Materials Express. 2017-04-01, 7 (2): 79–92 [2021-05-21]. ISSN 2158-5849. doi:10.1166/mex.2017.1357 （英语）.

[4] Eduardo Buxaderas, Marilyn Graziano-Mayer, María Volpe, Gabriel Radivoy. Bimetallic Cu-Pd Nanoparticles Supported on Bio-silica as an Efficient Catalyst for Selective Aerobic Oxidation of Benzylic Alcohols. Synthesis. 2016-10-21, 49 (06): 1387–1393 [2021-05-21]. ISSN 0039-7881. doi:10.1055/s-0036-1588628. （原始内容存档于2018-06-02）（英语）.

[5] Karol Kraszewski, Ireneusz Tomczyk, Aneta Drabinska, Krzysztof Bienkowski, Renata Solarska, Marcin Kalek. Mechanism of Iodine(III)‐Promoted Oxidative Dearomatizing Hydroxylation of Phenols: Evidence for a Radical‐Chain Pathway. Chemistry – A European Journal. 2020-09-04, 26 (50): 11584–11592 [2021-05-21]. ISSN 0947-6539. doi:10.1002/chem.202002026 （英语）.

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